反应详情

温度

70 °C

84 g of citric acid and 112 ml of concentrated sulfuric acid were stirred for one hour at ambient temperature and then heated progressively to 70° C. and maintained there for 35 minutes. The mixture was cooled to 0° C. and 34.56 g of 1,3-benzene diol and 44.8 ml of concentrated sulfuric acid were added. The mixture was maintained for 16 hours at 0° C. and then poured over ice. The crystallized product was separated off and dried under reduced pressure to obtain after crystallization from water, 22.77 g of the expected product melting at 210° C.

1. temperaturemaintained there for 35 minutes
2. temperatureThe mixture was cooled to 0° C.
3. temperatureThe mixture was maintained for 16 hours at 0° C.
4. additionpoured over ice
5. customThe crystallized product was separated off
6. customdried under reduced pressure
7. customto obtain
8. customafter crystallization from water, 22.77 g of the expected product melting at 210° C.