反应详情

45 g of the product of Step A, 10.3 g of boric acid and 1 g of p-toluenesulfonic acid were heated at 180° C. for 3 hours and the mixture was poured into ice and extracted with ethyl acetate. The mixture was decanted, dried and concentrated under reduced pressure and the residue was distilled to obtain 10.8 g of expected product.

1. additionthe mixture was poured into ice
2. extractionextracted with ethyl acetate
3. customThe mixture was decanted
4. customdried
5. concentrationconcentrated under reduced pressure
6. distillationthe residue was distilled