Hydrochloric Acid → HCID 178525221, compound

HRID 973822Notes

Reaction equation

HRID 973822 reaction equation
C([O:3][C:4]([CH2:6][C:7]1[CH:12]=[C:11]([SH:13])[N:10]2[N:14]=[CH:15][N:16]=[C:9]2[N:8]=1)=[O:5])C.[OH-].[K+].Cl>O>[C:4]([CH2:6][C:7]1[CH:12]=[C:11]([SH:13])[N:10]2[N:14]=[CH:15][N:16]=[C:9]2[N:8]=1)([OH:5])=[O:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 178470728HCID 178470728, compound

Product 1

HCID 178525221HCID 178525221, compoundYield 73.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
60 °C

Procedure

The product obtained in Step 3 (20 g) was added to a solution of 10 g of potassium hydroxide in 200 ml of water, the mixture was heated at 60° C. for two hours. After cooling the resulting yellow solution, its pH was lowered to 2.0 with concentrated hydrochloric acid, and the yellow crystals thus formed were collected by filtration, washed twice with 30 ml of water and dried, giving 13 g of the objective compound as yellow crystals.

Workup

  1. temperatureAfter cooling the resulting yellow solution, its pH
  2. customthe yellow crystals thus formed
  3. filtrationwere collected by filtration
  4. washwashed twice with 30 ml of water
  5. customdried

Sources & evidence

ORD record
ord-84646680586c4838923549129d849beb
Source dataset
uspto-grants-1991_11
Patent number
US05064953

Reaction notes

Loading…