Hydrochloric Acid → HCID 178499046, compound

HRID 973835Notes

Reaction equation

HRID 973835 reaction equation
Cl[C:2]1[N:7]2[N:8]=[C:9]([C:11]([O:13][CH3:14])=[O:12])[N:10]=[C:6]2[N:5]=[C:4]([CH3:15])[C:3]=1[CH3:16].[SH-:17].[Na+].Cl>O>[CH3:15][C:4]1[C:3]([CH3:16])=[C:2]([SH:17])[N:7]2[N:8]=[C:9]([C:11]([O:13][CH3:14])=[O:12])[N:10]=[C:6]2[N:5]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 28015Sodium hydrosulfideHCID 19989193HCID 19989193, compound

Product 1

HCID 178499046HCID 178499046, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The product obtained in Step 2 was added all at once at 0° C. to a solution of sodium hydrosulfide (40 g) in 800 ml of water with stirring under a nitrogen stream, the mixture was stirred at 0° C. for 30 minutes and then at room temperature for 1.5 hours, its pH was lowered to 2.0 with concentrated hydrochloric acid. The formed crystals were collected by filtration and washed with 300 ml of water and 200 ml of ethanol, affording 36 g of the objective compound as yellow crystals.

Workup

  1. stirringthe mixture was stirred at 0° C. for 30 minutes
  2. filtrationThe formed crystals were collected by filtration
  3. washwashed with 300 ml of water and 200 ml of ethanol

Sources & evidence

ORD record
ord-eeab659640bb4b118e3e7fc94b3f79b6
Source dataset
uspto-grants-1991_11
Patent number
US05064953

Reaction notes

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