HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 178499052, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate | HCID 77201 | — |
| Reactant | Butanoic acid, 3-thioxo-, ethyl ester | HCID 11744773 | — |
| Product | HCID 178499052 | HCID 178499052 | — |
Reaction Steps
A suspension of ethyl 2-methylthiocarbonylacetate (37.6 g) and 3-amino-5-methoxycarbonyl-s-triazole (20 g) in dimethylformamide (200 ml) was refluxed for one hour. After removing the solvent by distillation under reduced pressure, ether was added to the residue, and the formed crystals were purified by silica gel chromatography, giving 11.7 g of the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064953 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-e8f6ed2b3c85490084d93feb9ece9d92 |
| Source note | uspto-grants-1991_11 |