Hydrochloric Acid → HCID 178524741, compound

HRID 973847Notes

Reaction equation

HRID 973847 reaction equation
C([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[N:10]([N:13]=[C:14]([SH:16])[N:15]=2)[C:11]=1[OH:12])=[O:5])C.[OH-].[Na+].Cl>O>[C:4]([C:6]1[CH:7]=[N:8][C:9]2[N:10]([N:13]=[C:14]([SH:16])[N:15]=2)[C:11]=1[OH:12])([OH:5])=[O:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 178469698HCID 178469698, compound

Product 1

HCID 178524741HCID 178524741, compoundYield 99.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The product obtained in Step 1 of Example 48 (2.5 g) was added to a solution of 1.3 g sodium hydroxide dissolved in 20 ml of water and stirred at room temperature for four hours. The pH of the solution was adjusted to 1-2 with 6N hydrochloric acid. The formed crystals were collected by filtration, washed with 30 ml of water and dried, affording 2.2 g of the objective compound.

Workup

  1. filtrationThe formed crystals were collected by filtration
  2. washwashed with 30 ml of water
  3. customdried

Sources & evidence

ORD record
ord-5cba1d58dca94301a79c42fd2e02e3e0
Source dataset
uspto-grants-1991_11
Patent number
US05064953

Reaction notes

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