HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178469410, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium hydrosulfide | HCID 28015 | — |
| Reactant | 5-Chloro-7-ethoxycarbonyl-3-methyl-s-triazolo[4,3-a]pyrimidine | HCID 14850455 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178469410 | HCID 178469410 | 80.8% |
Reaction Steps
The product obtained in Step 2 (4.0 g) was added all at once under ice cooling to a solution of 4.0 g of sodium hydrosulfide in 100 ml of water with stirring in nitrogen, and the mixture was stirred at room temperature overnight. The resulting solution was acidified to pH 1.0 with 6N hydrochloric acid, and the separated crystals were collected by filtration and recrystallized from ethanol, affording 3.2 g of the objective compound as orange crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064953 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-657ec52b6ea14fa9839339d538bcdc3c |
| Source note | uspto-grants-1991_11 |