反应详情

The product obtained in Step 2 (4.0 g) was added all at once under ice cooling to a solution of 4.0 g of sodium hydrosulfide in 100 ml of water with stirring in nitrogen, and the mixture was stirred at room temperature overnight. The resulting solution was acidified to pH 1.0 with 6N hydrochloric acid, and the separated crystals were collected by filtration and recrystallized from ethanol, affording 3.2 g of the objective compound as orange crystals.

1. stirringthe mixture was stirred at room temperature overnight
2. filtrationthe separated crystals were collected by filtration
3. customrecrystallized from ethanol