Potassium Hydroxide → HCID 178524623, compound

HRID 973854Notes

Reaction equation

HRID 973854 reaction equation
[OH:1][C:2]1[N:7]2[C:8]([SH:11])=[N:9][N:10]=[C:6]2[N:5]=[C:4]([C:12]([O:14]C)=[O:13])[CH:3]=1.[OH-].[K+]>O>[C:12]([C:4]1[CH:3]=[C:2]([OH:1])[N:7]2[C:8]([SH:11])=[N:9][N:10]=[C:6]2[N:5]=1)([OH:14])=[O:13]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 178498582HCID 178498582, compound

Product 1

HCID 178524623HCID 178524623, compoundYield 92.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The product obtained in Step 1 (4.5 g) was added to a solution of 1.7 g potassium hydroxide in 50 ml water, and the mixture was refluxed for two hours. After cooling to room temperature, the solution was washed with 50 ml of ethyl acetate, the pH was adjusted to 1.0 with hydrochloric acid, and the formed crystals were collected by filtration, affording 3.9 g of the objective compound.

Workup

  1. temperaturethe mixture was refluxed for two hours
  2. washthe solution was washed with 50 ml of ethyl acetate
  3. filtrationthe formed crystals were collected by filtration

Sources & evidence

ORD record
ord-8ad0b0fb11e644bc8cd3e5b70784d2c8
Source dataset
uspto-grants-1991_11
Patent number
US05064953

Reaction notes

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