Potassium Hydroxide → HCID 178524747, compound

Participants

Reaction Conditions

Reaction Steps

The product obtained in Step 1 (9.1 g) was added to a solution of 4.0 g of potassium hydroxide in 200 ml of water, and the mixture was heated at 60° C. for 30 minutes. After cooling to room temperature, the solution was washed with 200 ml of ethyl acetate and the pH was adjusted to 1.0 with hydrochloric acid. The formed crystals were collected by filtration and washed with ether, affording 6.5 g of the objective compound.

Provenance & Evidence