Nitric Acid → HCID 19987116, compound

Participants

Reaction Conditions

Reaction Steps

25 g of 2-acetylamino-4-chlorobenzonitrile obtained in Step (3) above was added little by little to 200 ml of fuming nitric acid which had been cooled at 0° C. After the completion of the addition, the mixture was reacted for 30 minutes, and then the reaction solution was poured into 1 liter of ice water. The crystals thus-deposited were collected by filtration, washed thoroughly with water and dried. Yield: 22.2 g (72.4%).

Provenance & Evidence