反应详情

A stirred mixture of 2-(4-aminophenyl)-4H,6H-1,3,4-thiadiazin-5-one (1.0 g), 4H-pyran-4-one (0.51 g). water (20 ml ) and concentrated hydrochloric acid (0.42 ml), was heated under reflux for 3 hours. The warm solution was neutralised with concentrated aqueous ammonia and cooled to give a solid, 1.33 g. Recrystallisation from methanol gave the title compound, 0.89 g, m.p. 289-291° C.

1. temperatureunder reflux for 3 hours
2. temperaturecooled
3. customto give a solid, 1.33 g
4. customRecrystallisation from methanol