Hydrochloric Acid → N-(4-diethylamino-2-butynyl)-2-cyclohexyl-2-hydroxy-2-phenylacetamide hydrochloride

HRID 973992Notes

Reaction equation

HRID 973992 reaction equation
[CH2:1]([N:3]([CH2:25][CH3:26])[CH2:4][C:5]#[C:6][CH2:7][NH:8][C:9](=[O:24])[C:10]([CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1)([OH:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH3:2].[ClH:27]>C(Cl)(Cl)Cl>[ClH:27].[CH2:25]([N:3]([CH2:1][CH3:2])[CH2:4][C:5]#[C:6][CH2:7][NH:8][C:9](=[O:24])[C:10]([CH:18]1[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]1)([OH:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH3:26]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14931302N-(4-diethylamino-2-butynyl)-2-cyclohexyl-2-hydroxy-2-phenylacetamide

Product 1

HCID 19775499N-(4-diethylamino-2-butynyl)-2-cyclohexyl-2-hydroxy-2-phenylacetamide hydrochloride

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of N-(4-diethylamino-2-butynyl)-2-cyclohexyl-2-hydroxy-2-phenylacetamide (74 mg) in chloroform was added 4.1N methanolic hydrogen chloride (0.2 ml) and the mixture was evaporated in vacuo to give N-(4-diethylamino-2-butynyl)-2-cyclohexyl-2-hydroxy-2-phenylacetamide hydrochloride (90 mg) as oil.

Workup

  1. customthe mixture was evaporated in vacuo

Sources & evidence

ORD record
ord-90d3c527373b40eb99d5396d2347ac0d
Source dataset
uspto-grants-1991_11
Patent number
US05066680

Reaction notes

Loading…