Hydrochloric Acid → HCID 19775522, compound

HRID 974002Notes

Reaction equation

HRID 974002 reaction equation
[CH3:1][N:2]([CH3:26])[CH2:3][C:4]#[C:5][CH2:6][NH:7][C:8](=[O:25])[C:9]([CH2:22][CH:23]=[CH2:24])([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[ClH:27]>C(Cl)(Cl)Cl>[ClH:27].[CH3:26][N:2]([CH3:1])[CH2:3][C:4]#[C:5][CH2:6][NH:7][C:8](=[O:25])[C:9]([CH2:22][CH:23]=[CH2:24])([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14931319HCID 14931319, compound

Product 1

HCID 19775522HCID 19775522, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of N-(4-dimethylamino-2-butynyl)-2-allyl-2,2-diphenylacetamide (0.70 g) in chloroform (5ml) was added methanolic hydrogen chloride (0.15 g/ml, 0.4 ml) and the solution was evaporated in vacuo. The residue was crystallized from a mixture of diethyl ether and ethyl acetate and recrystallized from ethanol to give N-(4-dimethylamino-2-butynyl)-2-allyl-2,2-diphenylacetamide hydrochloride (0.65 g).

Workup

  1. customthe solution was evaporated in vacuo
  2. customThe residue was crystallized from a mixture of diethyl ether and ethyl acetate
  3. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-078e71abe7dc42c8a513d6f7b1406ed8
Source dataset
uspto-grants-1991_11
Patent number
US05066680

Reaction notes

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