Hydrochloric Acid → HCID 14817088, compound

HRID 974148Notes

Reaction equation

HRID 974148 reaction equation
C([NH:4][C:5]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[C:8]([NH:15]C(=O)C)=[CH:7][C:6]=1[N+:19]([O-:21])=[O:20])(=O)C.Cl>O>[NH2:4][C:5]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[C:8]([NH2:15])=[CH:7][C:6]=1[N+:19]([O-:21])=[O:20]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14817082HCID 14817082, compound

Product 1

HCID 14817088HCID 14817088, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
60 °C

Procedure

61 g (0.2 mol) of the 1,4-bisacetylamino-2-nitro-5-trifluoromethylbenzene prepared according to C. are heated at 98° C. together with 250 ml of water and 80 g of concentrated hydrochloric acid (36% strength), and the reaction mixture is stirred at this temperature for 2 hours. The mixture is then cooled to 60° C. and the pH is brought to 7.5 with an alkali. The mixture is now cooled to 5° C. and the product which has precipitated is filtered off with suction, washed with water and dried in a vacuum cabinet.

Workup

  1. temperatureThe mixture is now cooled to 5° C.
  2. customthe product which has precipitated
  3. filtrationis filtered off with suction
  4. washwashed with water
  5. customdried in a vacuum cabinet

Sources & evidence

ORD record
ord-2ab7df9eba72485c8d1b4efc0abbf239
Source dataset
uspto-grants-1991_11
Patent number
US05067967

Reaction notes

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