HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetonitrile → (4-Benzylpiperidin-1-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetonitrile | HCID 7856 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Benzylpiperidine | HCID 31738 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (4-Benzylpiperidin-1-yl)acetonitrile | HCID 10680164 | — |
Reaction Steps
40.8 ml of triethylamine and 22.2 g of chloroacetonitrile are dissolved in 180 ml of toluene, and 51.6 g of 4-benzylpiperidine are then added dropwise all at once.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068064 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-395d55e3a4ac4cca974c1bb33955e569 |
| Source note | uspto-grants-1991_11 |