反应详情

温度

80 °C

1,3-Disteroylglycerol. A mixture of 171.3 g (0.5 mole) glycidol stearate, 156.5 g (0.55 mole) stearic acid, 1.0 g (0.025 mole) sodium hydroxide, and tetrabutylammonium hydrogensulfate (8.5 g, 0.025 mole) in 400 mL ethanol is heated at reflux (80° C.) for 20 hours. The solid material is removed by passage of the reaction mixture through a short column of silica gel. After evaporation, the crude solid product is subjected to centrifugal partition chromatography using a mixture of acetonitrile-hexane. Recrystallization of the resulting powder from acetone-water gives 1,3-distearoylglycerol.

1. temperatureis heated
2. customThe solid material is removed by passage of the reaction mixture through a short column of silica gel
3. customAfter evaporation
4. customto centrifugal partition chromatography
5. additiona mixture of acetonitrile-hexane
6. customRecrystallization of the resulting powder from acetone-water