HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl formate → 4-(2-Aminoethyl)piperazine-1-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl formate | HCID 7865 | — |
| Reactant | Aminoethylpiperazine | HCID 8795 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(2-Aminoethyl)piperazine-1-carbaldehyde | HCID 14876000 | 48.2% |
Reaction Steps
Corresponding to Example 1, 774.3 g (6.00 mol) of N-2-aminoethylpiperazine in 300 ml of methanol were reacted with 120.0 g (2.00 mol) of methyl formate and 151.6 g (48% of theory) of N-2-aminoethyl-N'-formylpiperazine were obtained at 0.1 mm Hg between 115 and 120° C. in the form of a yellowish liquid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068264 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-acb735955c524fed9cd3a5e19811cb42 |
| Source note | uspto-grants-1991_11 |