HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 14876001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methacryloyl chloride | HCID 13528 | — |
| Reactant | 4-(2-Aminoethyl)piperazine-1-carbaldehyde | HCID 14876000 | — |
| Catalyst | 2,6-Di-tert-butyl-4-methylphenol | HCID 31404 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14876001 | HCID 14876001 | 44% |
Reaction Steps
117.9 g (0.75 mol) of N-2-aminoethyl-N'-formylpiperazine, 85.8 g (0.85 mol) of triethylamine and 100 mg of 2,6-di-tert.-butyl-4-methylphenol were reacted in 230 ml of dichloromethane with 78.4 g (0.75 mol) of methacryloyl chloride as described in Example 1 and the mixture was worked up. 73.9 g (44% of theory) of N-formyl-N'-(methacryloylaminoethyl)piperazine were obtained in this manner as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068264 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-80c1378b2dc1428292b69c9bee6f105d |
| Source note | uspto-grants-1991_11 |