Hydrochloric Acid → N-(5-(amino(2-chlorophenyl)methyl)-4-methylthiazol-2-yl)-1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide

HRID 97424Notes

Reaction equation

HRID 97424 reaction equation
[CH3:44][OH:45].[ClH:37].[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([C:10]1([C:13](=[O:14])[NH:15][c:16]3[s:17][c:18]([CH:22]([NH:23][S:24]([C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[c:30]4[c:31]([Cl:36])[cH:32][cH:33][cH:34][cH:35]4)[c:19]([CH3:21])[n:20]3)[CH2:11][CH2:12]1)[cH:9]2.[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([C:10]1([C:13](=[O:14])[NH:15][c:16]3[s:17][c:18]([CH:22]([NH2:23])[c:30]4[c:31]([Cl:36])[cH:32][cH:33][cH:34][cH:35]4)[c:19]([CH3:21])[n:20]3)[CH2:11][CH2:12]1)[cH:9]2

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 766727341-(1,3-benzodioxol-5-yl)-N-[5-[(tert-butylsulfinylamino)-(2-chlorophenyl)methyl]-4-methyl-1,3-thiazol-2-yl]cyclopropane-1-carboxamide

Product 1

HCID 76672719N-(5-(amino(2-chlorophenyl)methyl)-4-methylthiazol-2-yl)-1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide

Sources & evidence

ORD record
ord-0ff735491e2a4b7e9c425ee450384d22
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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