1-Methoxycarbonylmethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione → 1-Carboxymethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione

HRID 974260Notes

Reaction equation

HRID 974260 reaction equation
C[O:2][C:3]([CH2:5][N:6]1[C:15]2[CH2:14][CH2:13][CH2:12][C:11](=[O:16])[C:10]=2[CH:9]=[CH:8][C:7]1=[O:17])=[O:4]>[OH-].[Na+]>[C:3]([CH2:5][N:6]1[C:15]2[CH2:14][CH2:13][CH2:12][C:11](=[O:16])[C:10]=2[CH:9]=[CH:8][C:7]1=[O:17])([OH:4])=[O:2]

Participants

3

Reactant 1

HCID 199860021-Methoxycarbonylmethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione

Product 1

HCID 199859981-Carboxymethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Prepared by saponification from 1-methoxycarbonylmethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione in 1 N sodium hydroxide solution at room temperature. The reaction mixture was adjusted to pH 2 after two hours and extracted with ethyl acetate.

Workup

  1. extractionextracted with ethyl acetate

Sources & evidence

ORD record
ord-9e78e31439ec4c3194d8dd34d7971655
Source dataset
uspto-grants-1991_11
Patent number
US05068334

Reaction notes

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