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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 974260Generated: October 30, 2026

1-Methoxycarbonylmethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione → 1-Carboxymethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione

https://huagongshe.com/reaction/974260

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methoxycarbonylmethyl-7,8-dihydro-2,5(1H,6H)-quinolinedioneHCID 19986002—
SolventSodium HydroxideHCID 14798—
Product1-Carboxymethyl-7,8-dihydro-2,5(1H,6H)-quinolinedioneHCID 19985998—

Reaction Steps

Prepared by saponification from 1-methoxycarbonylmethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione in 1 N sodium hydroxide solution at room temperature. The reaction mixture was adjusted to pH 2 after two hours and extracted with ethyl acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05068334
Source datasetuspto-grants-1991_11
ORD IDord-9e78e31439ec4c3194d8dd34d7971655
Source noteuspto-grants-1991_11