Hydrochloric Acid → HCID 54190067, compound

HRID 974289Notes

Reaction equation

HRID 974289 reaction equation
Cl.C([NH:5][C:6]1[S:7][C:8]2[CH2:9][CH2:10][N:11]([CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:12][CH2:13][C:14]=2[N:15]=1)(=O)C.Cl>>[NH2:5][C:6]1[S:7][C:8]2[CH2:9][CH2:10][N:11]([CH2:16][CH:17]=[CH:18][C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH2:12][CH2:13][C:14]=2[N:15]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 19985941HCID 19985941, compound

Product 1

HCID 54190067HCID 54190067, compound

Procedure

Prepared from 2-acetylamino-6-(3-phenyl-propyl)-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine-hydrochloride with semi-concentrated hydrochloric acid. The foam obtained by evaporating to dryness is crystallised from concentrated ethanolic solution with the addition of a little acetone. Yield: 66% of theory, Melting point: 221°-225° C.

Workup

  1. customThe foam obtained
  2. customby evaporating to dryness
  3. customis crystallised from concentrated ethanolic solution with the addition of a little acetone

Sources & evidence

ORD record
ord-4f7f0f432cce475f9b0ffa44e5b8ff02
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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