2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine → HCID 53886359, compound

HRID 974318Notes

Reaction equation

HRID 974318 reaction equation
[CH3:1][C:2](=[CH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3]Cl.[NH2:12][C:13]1[S:14][C:15]2[CH2:16][CH2:17][NH:18][CH2:19][CH2:20][C:21]=2[N:22]=1>C(Cl)(Cl)Cl>[NH2:12][C:13]1[S:14][C:15]2[CH2:16][CH2:17][N:18]([CH2:3][C:2]([CH3:1])=[CH:5][C:6]3[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=3)[CH2:19][CH2:20][C:21]=2[N:22]=1

Participants

4

Reactant 2

HCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 54254060(3-Chloro-2-methylprop-1-en-1-yl)benzene

Product 1

HCID 53886359HCID 53886359, compoundYield 8%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 2-methyl-3-phenyl-allyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform for 2 hours at ambient temperature. Yield: 8% of theory, Melting point: 112°-115° C.

Sources & evidence

ORD record
ord-c31b1d4aa55a4b36bb95216cb90f4fb8
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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