HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 19985760, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Reactant | HCID 19985967 | HCID 19985967 | — |
| Catalyst | HCID 178479800 | HCID 178479800 | — |
| Solvent | Diethylamine | HCID 8021 | — |
| Product | HCID 19985760 | HCID 19985760 | — |
Reaction Steps
Prepared analogously to Example 10 from 2-amino-6-propargyl-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine, 4-bromo-benzonitrile and copper(I)iodide/bis(triphenyl-phosphine)palladium dichloride in diethylamine for 6 hours at ambient temperature. Yield: 46% of theory, Melting point: 174°-176° C. (acetone).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068325 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-a111f888be474c689cc97a7ececbb22e |
| Source note | uspto-grants-1991_11 |