HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 974400Generated: October 29, 2026
Potassium Carbonate → HCID 54346962, compound
https://huagongshe.com/reaction/974400
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N1-(2,4-Difluorobenzyl)-3-Chloro-2,2-Dimethylpropanamide | HCID 2779689 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 54346962 | HCID 54346962 | — |
Reaction Steps
49.7 g (0.19 mol) of 3-chloro-2,2-dimethyl-N-[(2,4-difluorophenyl)methyl]propanamide and 78.8 g (0.57 mol) of potassium carbonate are suspended in 200 ml of methyl ethyl ketone, and the suspension is warmed and stirred at 75° C. for 24 hours. When the reaction is complete (GC check), the mixture is filtered, and the filtrate is evaporated on a vacuum rotary evaporator. 40.9 g (95% of theory) of a yellow oil are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05068371 |
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| Source dataset | uspto-grants-1991_11 |
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| ORD ID | ord-3a4addd6971d49d5955b43b04fb7c208 |
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| Source note | uspto-grants-1991_11 |
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