Benzenesulfonic Acid → HCID 178511036, compound
Reaction equation
[S:1]([NH2:5])([NH2:4])(=[O:3])=[O:2].C1(S(O)(=O)=O)C=CC=CC=1.[Cl:16][CH2:17][CH2:18][C:19]#[N:20]>C(Cl)Cl.CC(C)=O>[S:1]([NH:5][C:19](=[NH:20])[CH2:18][CH2:17][Cl:16])(=[O:3])(=[O:2])[NH2:4]Participants
6
Reactant 3
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 57.5 °C
Procedure
Sulfamide (9.6 g, 0.1 mole) was added to a suspension of benzenesulfonic acid (31.6 g, 0.2 mole) in 3-chloropropionitrile (51.3 g, 0.6 mole). The suspension was heated at 55-60° C., for 18 hours. At the end of the heating period, the mixture was cooled to room temperature, diluted with methylene chloride (150 ml), and filtered. The solid, thus obtained, was suspended in acetone (50 ml), and the suspension filtered and the product dried.
Workup
- temperatureAt the end of the heating period, the mixture was cooled to room temperature
- filtrationfiltered
- customThe solid, thus obtained
- filtrationthe suspension filtered
- customthe product dried
Sources & evidence
- ORD record
- ord-aec0090170b24181864ee747aac77f2f
- Source dataset
- uspto-grants-1991_11
- Patent number
- US05068405
Reaction notes
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