反应详情

A 100-ml eggplant type flask was charged with 6.9 g (50 mmol) of 2,5-dimethylthiophenol, 5.5 g (60 mmol, 1.2 equivalents) of methallyl chloride which was a halogenated olefin, 6.9 g (50 mmol, 1 equivalent) of potassium carbonate and 30 ml of acetone, and the mixture was refluxed under heat for 1 hour. The reaction mixture was allowed to cool, insolubles were removed by filtration, and the acetone was distilled off. The resultant residue was re-dispersed in n-hexane and washed with a saturated sodium chloride aqueous solution. An organic layer was dried over anhydrous sodium sulfate, and then the solvent was distilled off to give 8.6 g (yield 89%) of 2-methyl-3-(2,5-dimethylphenylthio)propane.

1. temperaturethe mixture was refluxed
2. temperatureunder heat for 1 hour
3. temperatureto cool
4. custominsolubles were removed by filtration
5. distillationthe acetone was distilled off
6. additionThe resultant residue was re-dispersed in n-hexane
7. washwashed with a saturated sodium chloride aqueous solution
8. dry with materialAn organic layer was dried over anhydrous sodium sulfate
9. distillationthe solvent was distilled off