Morpholine → HCID 178473649, compound

Participants

Reaction Steps

Prepared by dropwise addition of one equivalent of morpholine to 6-allyloxycarbonyl-2-[1-[[trans-4-[[1-(ethoxycarbonyloxy)-ethyl]-oxycarbonyl]-cyclohexyl]aminocarbonyl]-piperid-4-yl]-4,5,7,8-tetrahydro-thiazolo[4,5-d]azepine and 0.1 equivalent of tetrakis-(triphenylphosphine)-palladium(O) in tetrahydrofuran followed by one hours' stirring at ambient temperature. The following compound is obtained analogously to Example 10:

Provenance & Evidence