HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 8-Benzyl-5-methyl2-oxa-5,8-diazabicyclo[4.3.0]nonane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Benzyl-4-hydroxy-3-(2-hydroxyethylmethyl-amino)-pyrrolidine | HCID 19969826 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 8-Benzyl-5-methyl2-oxa-5,8-diazabicyclo[4.3.0]nonane | HCID 15069984 | — |
Reaction Steps
18 g (71.9 mmol) of 1-benzyl-4-hydroxy-3-(2-hydroxyethyl-methyl-amino)-pyrrolidine are reacted in 60 ml of concentrated sulphuric acid and 30 ml of water as in Example F a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05607942 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-3e72ae7a181043d4b3fa48ac57d6a463 |
| Source note | uspto-grants-1997_03 |