3-Bromothiophene → 1-(2,4-Dimethyl-5-oxazolyl)-1-(3-thienyl)ethanol

HRID 975051Notes

Reaction equation

Br[C:2]1[CH:6]=[CH:5][S:4][CH:3]=1.CC1N=C(C)OC=1.[C:14]([C:17]1[O:21][C:20]([CH3:22])=[N:19][C:18]=1[CH3:23])(=[O:16])[CH3:15]>>[CH3:22][C:20]1[O:21][C:17]([C:14]([C:2]2[CH:6]=[CH:5][S:4][CH:3]=2)([OH:16])[CH3:15])=[C:18]([CH3:23])[N:19]=1

Participants

Reactant 2

HCID 133833-Bromothiophene

HCID 19970895HCID 19970895, compound

Product 1

HCID 189363541-(2,4-Dimethyl-5-oxazolyl)-1-(3-thienyl)ethanol

Procedure

Starting with 3-bromothiophene and 5-acetyl-2,4-dimethyloxazole dimethyloxazole and following the general method of Example 4 the title compound was prepared. M.p. 132°-133° C.

Sources & evidence

ORD record: ord-325adb8b8a1944a9b9b367016f6236ba
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05607956

Reaction notes

Loading…