反应详情

In anhydrous THF (80 ml) was dissolved α,α-diphenyl-γ-butyrolactone (7 g) followed by addition of lithium aluminum hydride (1 g) with ice-cooling, and the mixture was stirred under the same conditions for 3 hours. Then, under ice-cooling, a saturated aqueous solution of Rochelle salt was added dropwise to precipitate the aluminum and other inorganic matter. The supernatant was taken by decantation, dried and concentrated under reduced pressure. The residue was recrystallized from isopropyl ether to provide 2,2-diphenyl-1,4-butanediol (7 g).

1. temperaturecooling
2. temperatureThen, under ice-cooling
3. customto precipitate the aluminum and other inorganic matter
4. customdried
5. concentrationconcentrated under reduced pressure
6. customThe residue was recrystallized from isopropyl ether