HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Buten-2-ol → 5-(3-Hydroxy-1-but-1-enyl)-3-(N-methyl-4-piperidyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Buten-2-ol | HCID 11716 | — |
| Reactant | 5-bromo-3-(1-methylpiperidin-4-yl)-1H-indole | HCID 15745344 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-(3-Hydroxy-1-but-1-enyl)-3-(N-methyl-4-piperidyl)-1H-indole | HCID 54086563 | — |
Reaction Steps
Obtained by a procedure similar to that described in Example 1, using 5-bromo-3-(N-methyl-4-piperidyl)-1H-indole (EP-A-0303507) and but-3-en-2-ol, as a foam. Rf 0.50 (SS 4). Found: C,72.85; H,8.22; N,9.17. C18H24N2O; 0.17 CH2Cl2 requires C,73.08; H,8.22; N,9.38%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05607960 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-4a1b766f7e0f4601935c4348928aa0dd |
| Source note | uspto-grants-1997_03 |