Potassium Carbonate → 2-Phenyl-2-pentenal oxime

HRID 975250Notes

Reaction equation

HRID 975250 reaction equation
[Cl-].[OH:2][NH3+:3].C(=O)([O-])[O-].[K+].[K+].[C:10]1([C:16](=[CH:19][CH2:20][CH3:21])[CH:17]=O)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C(O)C>[C:10]1([C:16](=[CH:19][CH2:20][CH3:21])[CH:17]=[N:3][OH:2])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 21645Hydroxylamine HClHCID 30838052-Phenylpent-2-enal

Product 1

HCID 867504432-Phenyl-2-pentenal oximeYield 75.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of hydroxylammonium chloride (10.84 g, 0.156 mol) and potassium carbonate (21.56 g, 156 mmol) in absolute ethanol (100 ml) was stirred for 2 h. The precipitated sodium chloride was filtered off and 2-phenyl-2-pentenal (5.00 g, 31 mmol) was added to the filtrate. The mixture was stirred at ambient temperature for 16 h. The solvent was evaporated in vacuo, the residue was crystallised from aqueous ethanol to give 4.09 g 2-phenyl-2-pentenal oxime.

Workup

  1. filtrationThe precipitated sodium chloride was filtered off
  2. stirringThe mixture was stirred at ambient temperature for 16 h
  3. customThe solvent was evaporated in vacuo
  4. customthe residue was crystallised from aqueous ethanol

Sources & evidence

ORD record
ord-3ea8e6aa83b34472b573de0558a7cb6d
Source dataset
uspto-grants-1997_03
Patent number
US05608069

Reaction notes

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