反应详情

A mixture of potassium cyanide (2.0 g, 31 mmol), 4-fluorobenzaldehyde, 96% ethanol (30 ml) and water (30 ml) was heated at reflux for 0.5 h and then kept at 5° C. for 72 h. The precipitated compound was collected and recrystallised from ethanol/water to give 20 g of 2-hydroxy-1,2-bis(4-fluorophenyl)ethanone.

1. temperaturewas heated
2. temperatureat reflux for 0.5 h
3. customThe precipitated compound was collected
4. customrecrystallised from ethanol/water