2-Methoxyethylamine → HCID 19970607, compound

Participants

Reaction Steps

0.5 g (1.61 mmol) of methyl 5-[(4-fluorophenylsulfonyl)amino]pyridine-2-carboxylate (compound from Example 4a) is stirred at 70° C. for 3 h in 5 ml of 2-methoxyethylamine. The mixture is concentrated, the residue is dissolved in water, the solution is acidified with conc. HCl, the solid is filtered off with suction and washed with water and 0.53 g of the title compound is obtained in the form of colorless crystals, M.p. 154° C.

Provenance & Evidence