Ammonium Chloride → HCID 67705500, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of (2R,4S)-1-allyloxycarbonyl-2-(2-imino-2-methylthioethyl)-4-(triphenylmethylthio)pyrrolidine (1.95 g) in methanol (39 ml) was added ammonium chloride (222 mg). After stirring at 50° C. for 2 hours, the solution was evaporated under reduced pressure. The residue was triturated with diisopropyl ether to give (2R,4S)-1-allyloxycarbonyl-2-amidinomethyl-4-(triphenylmethylthio)pyrrolidine hydrochloride (1.36 g).

Provenance & Evidence