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HRID975711

反应详情

EQUATION

反应方程式

HRID 975711 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)[O-].[K+]
HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

结构：C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1CCn1cnc(C#N)c1
HCID53735347

未命名化合物

结构：CC(O)=S
HCID178418634

未命名化合物

PRODUCTS

生成物

1
结构：C=CCOC(=O)N1C[C@@H](SC(C)=O)C[C@H]1CCn1cnc(C#N)c1
HCID53670605

未命名化合物

PROCEDURE

实验过程

(2R,4R)-1-Allyloxycarbonyl-2-[2-(4-cyanoimidazol-1-yl) ethyl]-4-methanesulfonyloxypyrrolidine (13.4 g) was reacted with thioacetic acid (5.46 ml) and potassium t-butoxide (8.17 g) in substantially the same manner as Preparation 4-12) to give (2R,4S)-1-allyloxycarbonyl-4-acetylthio-2-[2-(4-cyanoimidazol-1-yl)ethyl]pyrrolidine (12.5 g) as a yellow paste.

WORKUP

后处理

  1. customas Preparation 4-12)