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HRID975809

反应详情

EQUATION

反应方程式

HRID 975809 的结构方程式

REACTANTS

反应物

6
结构：[I-].[K+]
HCID4875

Potassium iodide

IK

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CC(C)c1ccc(CCl)cc1
HCID74916

4-Isopropylbenzyl chloride

C10H13Cl

结构：CC(C)(C)OC(=O)N[C@H](CO)C(=O)O
HCID637603

Boc-D-serine

C8H15NO5

结构：CC(C)(C)OC(=O)N[C@H]1COc2ccccc2NC1=O
HCID18599719

未命名化合物

结构：CC(C)(C)OC(=O)N[C@@H]1COc2ccccc2NC1=O
HCID54323944

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)c1ccc(CN2C(=O)[C@H](NC(=O)OC(C)(C)C)COc3ccccc32)cc1
HCID54070159

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

Obtained analogously to the directions in Example 1a) starting from 4.8 g of (R)-3-(tert-butoxycarbonyl-amino)-2,3-dihydro-1,5-benzoxazepin-4-one (prepared analogously to (S)-3-(tert-butoxycarbonylamino)-2,3-dihydro-1,5-benzoxazepin-4-one, starting from N-Boc-(D)-serine), 4.4 g of p-isopropylbenzyl chloride, 2.9 g of potassium carbonate and 166 mg of potassium iodide. Rf value (eluant: hexane/ethyl acetate 4:1): 0.33.

WORKUP

后处理

  1. customObtained analogously to the directions in Example 1a)