Boron, trihydro(thiobis(methane))-, (T-4)- → 9,10-dihydro-4H-pyrrolo[1,2-a]thieno[2,3-e][1,4]diazepine

HRID 975851Notes

Reaction equation

HRID 975851 reaction equation
O=[C:2]1[NH:8][C:7]2[S:9][CH:10]=[CH:11][C:6]=2[CH2:5][N:4]2[CH:12]=[CH:13][CH:14]=[C:3]12.[B].CSC>>[S:9]1[C:7]2[NH:8][CH2:2][C:3]3[N:4]([CH:12]=[CH:13][CH:14]=3)[CH2:5][C:6]=2[CH:11]=[CH:10]1

Participants

3

Reactant 2

HCID 9833925Boron, trihydro(thiobis(methane))-, (T-4)-HCID 110418649-oxo-9,10-dihydro-4H-pyrrolo[1,2-a]-thieno[2,3-e][1,4]diazepine

Product 1

HCID 218371599,10-dihydro-4H-pyrrolo[1,2-a]thieno[2,3-e][1,4]diazepine

Procedure

The synthesis of 9-oxo-9,10-dihydro-4H-pyrrolo[1,2-a]thieno[2,3-e][1,4]diazepine is reported by A. Daich and B. Decroix, Bull. Soc. Chim. Fr 129, 360(1992); ##STR104## and is reduced with boron-dimethylsulfide to give 9,10-dihydro-4H-pyrrolo [1,2-a]thieno [2,3-e][1,4]diazepine. ##STR105##

Sources & evidence

ORD record
ord-deb72b1486a1402fba731c855093e59f
Source dataset
uspto-grants-1997_03
Patent number
US05610156

Reaction notes

Loading…