Hydrochloric Acid → HCID 1549172, compound

HRID 976017Notes

Reaction equation

HRID 976017 reaction equation
[NH2:1][C@@H:2]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C@H:13]([NH2:18])[C:14]([O:16]C)=[O:15])[C:3]([O:5]C)=[O:4].Cl>>[NH2:1][C@@H:2]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C@H:13]([NH2:18])[C:14]([OH:16])=[O:15])[C:3]([OH:5])=[O:4]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 57263921HCID 57263921, compound

Product 1

HCID 1549172HCID 1549172, compound

Conditions

Temperature
60 °C

Procedure

Dimethyl (S,S)-2,9-diaminodecanedioate (1.40g, 5.38 mmol) was dissolved in 6N HCl (40 ml, 240 mmol), and stirred under N2 at 60° C. for 12 hours. The solvent was evaporated, the residue dissolved in EtOH and crystallized by the addition of diethyl ester. The crystals were filtered off.

Workup

  1. customThe solvent was evaporated
  2. dissolutionthe residue dissolved in EtOH
  3. customcrystallized by the addition of diethyl ester
  4. filtrationThe crystals were filtered off

Sources & evidence

ORD record
ord-2261c25eea854b879c730ba1d6792e5e
Source dataset
uspto-grants-1997_03
Patent number
US05610141

Reaction notes

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