反应详情

温度

50 °C

To a mechanically stirred solution of meso-2,3-dibromosuccinic acid (27.6 g, 0.100 mol) in alcohol (200 ml) was slowly added benzylamine (85 g, 0.80 mol) at ambient temperature. After complete addition the mixture was refluxed overnight. A heavy precipitate of salts appeared. The mixture was cooled to 50° C. and concentrated hydrochloric acid was added until pH was 4-5. The precipitate was filtered off, washed several times with water and alcohol and dried.

1. customat ambient temperature
2. additionAfter complete addition the mixture
3. temperaturewas refluxed overnight
4. filtrationThe precipitate was filtered off
5. washwashed several times with water and alcohol
6. customdried