Thionyl Chloride → HCID 15177067, compound

HRID 976050Notes

Reaction equation

HRID 976050 reaction equation
[C:1]1([CH2:11][CH:12]([CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:13](O)=[O:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.O=S(Cl)[Cl:25]>>[C:1]1([CH2:11][CH:12]([CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:13]([Cl:25])=[O:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 15177066HCID 15177066, compound

Product 1

HCID 15177067HCID 15177067, compoundYield 100%

Procedure

A solution of 1.5 9 (5.2 mmol) of 2-(1-naphthylmethyl)-2-benzylacetic acid in 10 mL SOCl2 was stirred at room temperature overnight. The SOCl2 was removed under reduced pressure, the residue taken up in Et2O, and the solvent again removed under reduced pressure to give 1.6 g (100% yield) of the product as an oil.

Workup

  1. customThe SOCl2 was removed under reduced pressure
  2. customthe solvent again removed under reduced pressure

Sources & evidence

ORD record
ord-0a518134b5ac498c998a3e5976ff3813
Source dataset
uspto-grants-1997_03
Patent number
US05610177

Reaction notes

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