HCID 70279824, compound → HCID 19968956, compound

Participants

Reaction Steps

To 6.74 g of (E)-4-[3-(1-acetylpiperidin-4-yl)propenoyl]nitrobenzene were added 300 ml of methanol and 0.30 g of platinum oxide, and under a hydrogen stream, the mixture was stirred at room temperature for 3 hours. Then, the solid was removed by filtration, the solvent was removed by distillation under reduced pressure, and the obtained residue was applied to silica gel column chromatography to obtain 4.81 g of the title compound as brownish white powder.

Provenance & Evidence