Trifluoroacetic acid → HCID 86750555, compound

Participants

Reaction Steps

30 ml of chloroform was added to 2.07 g of N-t-butoxy-carbonyl-4-[(1-benzyl-4-hydroxypiperidin-4-yl)acetyl]aniline, trifluoroacetic acid was added thereto three times in a total amount of 8 ml, and the mixture was stirred at room temperature. Thereafter, the solvent was removed by distillation under reduced pressure, and the obtained residue was applied to silica gel column chromatography to obtain 1.14 g of the title compound as reddish white powder.

Provenance & Evidence