HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → 4-Methoxy-6-(trifluoromethyl)pyrimidin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 4-Chloro-6-(trifluoromethyl)pyrimidin-2-amine | HCID 13086907 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Methoxy-6-(trifluoromethyl)pyrimidin-2-amine | HCID 606193 | — |
Reaction Steps
2-Amino-4-ethoxy-6-trifluoromethylpyrimidine of melting point 114°-116° C. was obtained in a similar manner by reacting 2-amino-4-chloro-6-trifluoromethylpyrimidine with sodium methylate in ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05612286 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-9fddfb9c29874201b6361c4dfe7c53b0 |
| Source note | uspto-grants-1997_03 |