Hydrochloric Acid → HCID 19966772, compound

Participants

Reaction Steps

The resulting 3-(4-chloro-5-cyclopentyloxy-2-fluorophenyl)-4-imino-5-isopropylideneoxazolidine-2-one was dissolved in toluene and conc. HCl (ca. 2 eq.) was added to the solution at room temperature; the mixture was stirred thoroughly and the resulting white solids was subjected to filtration, washed thoroughly with toluene and hexane and subsequently dried to yield 3-(4-chloro-5-cyclopentyloxy-2-fluorophenyl)-4-imino-5-isopropylideneoxazolidine-2-one hydrochloride (compound 1) almost quantitatively.

Provenance & Evidence