98061-65-5 → HCID 86750586, compound

HRID 976477Notes

Reaction equation

HRID 976477 reaction equation
Br[CH2:2]/[C:3](=[CH:7]\[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)/[C:4]([OH:6])=[O:5].[C:14]([OH:22])(=[S:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:14]([S:21][CH2:2]/[C:3](=[CH:7]\[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)/[C:4]([OH:6])=[O:5])(=[O:22])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 602327098061-65-5HCID 178526132HCID 178526132, compound

Product 1

HCID 86750586HCID 86750586, compoundYield 67%

Procedure

The (Z)-2-bromomethyl-3-phenylpropenoic acid described in Example 1 (step A) is reacted with thiobenzoic acid according to the experimental procedure described in Example 1 (step B). Yield=67% (recrystallized in ether) m.p. 160° C. 1H NMR CDCl3 /TMS): 8.15 to 7.80 (m, 3H); 7.70 to 7.20 (m, 8H); 4.20 (s, 2H)

Workup

  1. customYield=67% (recrystallized in ether) m.p. 160° C

Sources & evidence

ORD record
ord-0ceeb50cb90e469a8848071a270744aa
Source dataset
uspto-grants-1997_03
Patent number
US05612371

Reaction notes

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