Propionic anhydride → HCID 12636967, compound

HRID 976492Notes

Reaction equation

[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH:12]=O)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16]([O:20]C(=O)CC)(=[O:19])[CH2:17][CH3:18]>>[CH3:18]/[C:17](=[CH:12]\[C:11]1[CH:14]=[CH:15][C:8]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:9][CH:10]=1)/[C:16]([OH:20])=[O:19]

Participants

Reactant 2

HCID 31263Propionic anhydride

HCID 661394-Phenoxybenzaldehyde

Product 1

HCID 12636967HCID 12636967, compoundYield 68%

Procedure

The procedure is performed in an analogous manner to that described in Example 17 (step A), starting from 4-phenoxybenzaldehyde and using 5 equivalents of propionic anhydride. Yield: 68% IR (nujol): 1665 cm-1 m.p. 133° C. 1H NMR (CDCl3 /TMS): 11.95 (broad s, 1H); 7.80 (s, 1H); 7.60 to 6.85 (m, 9H); 2.15 (s, 3H).

Workup

custom133° C

Sources & evidence

ORD record: ord-36e3df3e7f4e4fcdb2386b31697b456b
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05612371

Reaction notes

Loading…