反应详情

温度

100 °C

A mixture of the sulfoxide (50 mg) from Step 3 and cyclopentylamine (1 mL) was stirred at 100° C. overnight. Excess cyclopentylamine was removed and the residue was purified by preparative TLC (25% EtOAc/hexanes) to give the desired product (26 mg). MS: 307.3 (M+H).

1. customExcess cyclopentylamine was removed
2. customthe residue was purified by preparative TLC (25% EtOAc/hexanes)